Presenilin 1 Polyclonal Antibody

calcium channel activity PDZ domain binding aspartic endopeptidase activity, intramembrane cleaving endopeptidase activity aspartic-type endopeptidase activity protein binding beta-catenin binding peptidase activity cadherin binding ATPase binding binding, bridging growth factor receptor binding aspartic protease

autophagosome assembly negative regulation of transcription from RNA polymerase II promoter activation of MAPKK activity blood vessel development cell fate specification somitogenesis neuron migration positive regulation of receptor recycling heart looping positive regulation of L-glutamate transport hematopoietic progenitor cell differentiation astrocyte activation involved in immune response T cell activation involved in immune response protein glycosylation membrane protein ectodomain proteolysis mitochondrial transport cellular response to DNA damage stimulus response to oxidative stress negative regulation of epidermal growth factor-activated receptor activity Notch signaling pathway memory post-embryonic development regulation of neuron projection development protein transport choline transport synaptic vesicle targeting protein processing cerebral cortex cell migration Cajal-Retzius cell differentiation dorsal/ventral neural tube patterning embryonic limb morphogenesis positive regulation of protein binding positive regulation of proteasomal ubiquitin-dependent protein catabolic process endoplasmic reticulum calcium ion homeostasis beta-amyloid formation intracellular signal transduction positive regulation of protein import into nucleus positive regulation of tumor necrosis factor biosynthetic process amyloid precursor protein metabolic process myeloid dendritic cell differentiation positive regulation of apoptotic process positive regulation of catalytic activity skin morphogenesis positive regulation of glycolytic process positive regulation of transcription, DNA-templated regulation of synaptic plasticity thymus development neuron development skeletal system morphogenesis brain morphogenesis epithelial cell proliferation negative regulation of axonogenesis synapse organization positive regulation of coagulation T cell receptor signaling pathway neuron apoptotic process negative regulation of ubiquitin-protein transferase activity regulation of synaptic transmission, glutamatergic regulation of resting membrane potential regulation of canonical Wnt signaling pathway positive regulation of dendritic spine development calcium ion transmembrane transport modulation of age-related behavioral decline cell-cell adhesion cellular response to beta-amyloid negative regulation of core promoter binding positive regulation of amyloid fibril formation neuron projection maintenance negative regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process negative regulation of apoptotic signaling pathway neural retina development Notch receptor processing learning or memory regulation of gene expression positive regulation of gene expression negative regulation of gene expression cerebellum development membrane protein intracellular domain proteolysis positive regulation of tumor necrosis factor production amyloid precursor protein catabolic process negative regulation of apoptotic process negative regulation of neuron apoptotic process astrocyte activation calcium ion homeostasis regulation of synaptic vesicle cycle regulation of postsynapse organization protein catabolic process at postsynapse negative regulation of protein phosphorylation positive regulation of protein phosphorylation myeloid leukocyte differentiation negative regulation of protein kinase activity cellular calcium ion homeostasis autophagy brain development heart development glycoprotein biosynthetic process gene expression cerebral cortex development neurogenesis neuron differentiation forebrain development segmentation locomotion negative regulation of epidermal growth factor receptor signaling pathway eye photoreceptor cell development positive regulation of MAP kinase activity positive regulation of protein kinase activity beta-amyloid metabolic process smooth endoplasmic reticulum calcium ion homeostasis protein maturation L-glutamate import across plasma membrane synaptic vesicle transport long-term synaptic potentiation