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Invitrogen
Procaine Recombinant Mouse Monoclonal Antibody (5F12)
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Procaine Antibody (MA566357) in SDS-PAGE
SDS-PAGE characterization of Procaine under reducing conditions. Lane M: Protein marker (kDa); Lane PRC: Purified Procaine Recombinant Monoclonal (Product # MA566357). Procaine showing heavy chain (~50 kDa) and light chain (~25 kDa). Gels were stained with Coomassie Brilliant Blue R-626.
产品信息
MA566357
产品规格
种属反应
Chemical
宿主/亚型
Mouse
/ IgG
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
5F12
抗原
Conjugate of PRC hapten and KLH.
偶联物
形式
Liquid
浓度
7 mg/mL
纯化类型
Protein G
保存液
PBS
内含物
0.09% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
Procaine is a local anesthetic that has been widely used since its discovery in 1905. It is characterized by a slow onset and rapid degradation into para-aminobenzoic acid and diethylaminoethanol, resulting in a brief half-life and short duration of action. Procaine's chemical structure includes an ester linkage, which is hydrolyzed by plasma esterases, contributing to its short duration. Despite its rapid degradation, procaine has been investigated for various modifications to enhance its dissolution rate and permeability without altering its chemical structure. Additionally, procaine has been explored for its potential as a geroprotector due to its historical use in anti-aging treatments. Recent studies have focused on synthesizing novel procaine derivatives to improve its pharmacodynamic properties for intravenous anesthesia. Procaine also acts as a specific inhibitor of DNA methyltransferase, which has led to the development of procaine-based transition metal complexes for potential therapeutic applications.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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