Invitrogen

Procollagen I N-Peptide Monoclonal Antibody (C6)

Name: Procollagen I N-Peptide Monoclonal Antibody (C6)
Brand: Invitrogen
SKU: MA5-41662

查看其他4个Procollagen I N-Peptide抗体

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

说明书

证书

实验方案

问题与答案

技术支持

Additional Information:

抗体检测数据 (1)

Procollagen I N-Peptide Antibody in Western Blot (WB)

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Procollagen I N-Peptide Antibody (MA5-41662) in WB

Western blot analysis of Procollagen I C-Peptide in recombinant human PINP. Sample was incubated with monoclonal antibody (Product # MA5-41662).

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Immunogen image

Immunogen Image Procollagen I N-Peptide Monoclonal Antibody (C6)

产品信息

MA5-41662

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.01-5 µg/mL

免疫组化（石蜡） (IHC (P))

5-50 µg/mL

产品规格

种属反应

Human, Rat

宿主/亚型

Mouse / IgG1, kappa

分类

Monoclonal

类型

Antibody

克隆号

抗原

Recombinant protein Procollagen I N-Terminal Propeptide

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

1 mg/mL

200 µg

纯化类型

Protein A/G

保存液

PBS, pH 7.4, with 50% glycerol

内含物

0.05% ProClin 300

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2899144

靶标信息

Procollagen type I N-terminal propeptide (P1NP) is a specific marker of bone formation, reflecting the synthesis of type I collagen, which constitutes the major part of the bone matrix. P1NP is derived during the conversion of procollagen to collagen, produced by osteoblasts during bone formation. Its primary clinical application lies in the diagnosis and monitoring of metabolic bone diseases, particularly osteoporosis. In osteoporotic patients, P1NP levels can predict bone mineral density (BMD) responses to treatments like teriparatide and romosozumab. Low serum levels of P1NP are indicative of a high risk of BMD loss, providing a valuable tool for premenopausal women with systemic lupus erythematosus (SLE) and other conditions affecting bone health.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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生物信息学

蛋白别名: alpha 1 (I) chain propeptide; alpha-1 collagen type 1; alpha-1 collagen type I; Alpha-1 type I collagen; alpha1(I) procollagen; COL1A1; collagen alpha 1 chain type I; Collagen alpha-1(I) chain; collagen alpha-1(I) chain preproprotein; collagen Col1-ColIII-1; collagen Col1-ColIII-2; collagen of skin, tendon and bone, alpha-1 chain; collagen, type 1, alpha 1; collagen, type I, alpha 1; P1NP; pro-alpha-1 collagen type 1; Procollagen I N; procollagen type I, alpha 1; procollagen, type 1, alpha 1; type I proalpha 1; type I procollagen alpha 1 chain; type I-alpha 1 collagen; unnamed protein product

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基因别名: CAFYD; COL1A1; COLIA1; EDSARTH1; EDSC; OI1; OI2; OI3; OI4

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UniProt ID: (Human) P02452, (Rat) P02454

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Entrez Gene ID: (Human) 1277, (Rat) 29393

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功能

protease binding extracellular matrix structural constituent protein binding extracellular matrix structural constituent conferring tensile strength identical protein binding metal ion binding platelet-derived growth factor binding molecular_function extracellular matrix structural protein

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