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MA1-43034 detects Prothrombin in mouse samples. In Western blot, this antibody only detects the non-reduced protein with an expected molecular weight of 72kDa.
MA1-43034 was derived from mouse prothrombin.
Prothrombin or Coagulation factor II, is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Coagulation factor II; Prothrombin
基因别名: Cf-2; Cf2; F2; FII
UniProt ID: (Mouse) P19221
Entrez Gene ID: (Mouse) 14061