Invitrogen

Prothrombin Monoclonal Antibody (Ca-Pro 20), Biotin

查看其他26个Prothrombin抗体

问题与答案

问题与答案

问题与答案

Immunogen image

Prothrombin Monoclonal Antibody (Ca-Pro 20), Biotin

Immunogen Image Prothrombin Monoclonal Antibody (Ca-Pro 20), Biotin

产品信息

MA5-17630

应用

建议稀释比

已发表文章

免疫印迹 (WB)

Assay-dependent

-

酶联免疫吸附实验 (ELISA)

Assay-dependent

-

产品规格

种属反应

Human

宿主/亚型

Mouse / IgG1

分类

Monoclonal

类型

Antibody

克隆号

Ca-Pro 20

抗原

Human Prothrombin (CaPro-20) purified from plasma.

查看免疫原

偶联物

Biotin Biotin Biotin

形式

Liquid

浓度

0.1 mg/mL

纯化类型

Protein G

保存液

PBS with 4-5mg/mL BSA

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

产品详细信息

MA5-17630 targets Prothrombin in ELISA and WB applications and shows reactivity with Human samples.

The MA5-17630 immunogen is human Prothrombin (CaPro-20) purified from plasma.

靶标信息

Prothrombin or Coagulation factor II, is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

篇参考文献 (0)

您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。

引用该产品

生物信息学

蛋白别名: Coagulation factor II; coagulation factor II (thrombin); prepro-coagulation factor II; Prothrombin; prothrombin B-chain; serine protease

查看更多收起

基因别名: F2; PT; RPRGL2; THPH1

查看更多收起

UniProt ID: (Human) P00734

查看更多收起

Entrez Gene ID: (Human) 2147

查看更多收起

serine-type endopeptidase activity receptor binding calcium ion binding protein binding growth factor activity thrombospondin receptor activity protease serine protease protein modifying enzyme

positive regulation of protein phosphorylation signal peptide processing proteolysis ER to Golgi vesicle-mediated transport acute-phase response cell surface receptor signaling pathway multicellular organism development blood coagulation blood coagulation, intrinsic pathway positive regulation of cell proliferation regulation of cell shape response to wounding regulation of gene expression negative regulation of platelet activation positive regulation of phosphatidylinositol 3-kinase signaling response to inactivity peptidyl-glutamic acid carboxylation platelet activation regulation of blood coagulation positive regulation of blood coagulation positive regulation of cell growth positive regulation of collagen biosynthetic process fibrinolysis cellular protein metabolic process negative regulation of proteolysis negative regulation of astrocyte differentiation leukocyte migration positive regulation of release of sequestered calcium ion into cytosol regulation of cytosolic calcium ion concentration negative regulation of fibrinolysis cellular response to mechanical stimulus positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway positive regulation of reactive oxygen species metabolic process