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Abnova
RAB3A Monoclonal Antibody (4H7)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00005864-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
4H7
抗原
RAB3A (NP_002857, 122 a.a. approximately 220 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: TYSWDNAQVL LVGNKCDMED ERVVSSERGR QLADHLGFEF FEASAKDNIN VKQTFERLVD VICEKMSESL DTADPAVTGA KQGPQLSDQQ VPPHQDCAC
靶标信息
Rab proteins belong to the Ras small GTPase superfamily. The GTP-binding Rab3 subfamily has 4 known isoforms: 3A, 3B, 3C, and 3D. These proteins are expressed in highest concentrations in brain and endocrine tissues and involved in regulated exocytosis of hormones and neurotransmitters. Specifically, Rab 3s are thought to play a key role in presynaptic vesicle trafficking and priming.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: C18A3.6; RAS-associated protein RAB3A; unnamed protein product
基因别名: SCA52
UniProt ID: (Human) P20336
Entrez Gene ID: (Human) 5864
plasma membrane repair
exocytosis
axonogenesis
synaptic vesicle exocytosis
calcium ion regulated exocytosis
insulin secretion
regulation of synaptic vesicle fusion to presynaptic membrane
lysosome localization
synaptic vesicle recycling
constitutive secretory pathway
regulated exocytosis
positive regulation of exocytosis
regulation of short-term neuronal synaptic plasticity
synaptic vesicle transport
acrosomal vesicle exocytosis
evoked neurotransmitter secretion
synaptic vesicle clustering
regulation of presynaptic dense core granule exocytosis
positive regulation of regulated secretory pathway
regulation of plasma membrane repair
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
