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Invitrogen
RAB3GAP2 Polyclonal Antibody
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RAB3GAP2 Antibody (PA5-116763) in WB
Western blot analysis of RAB3GAP2 in extracts of various cell lines. Samples were incubated with RAB3GAP2 Polyclonal antibody (Product # PA5-116763) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-116763
产品规格
种属反应
Human,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human RAB3GAP2 (NP_0365462)
偶联物
形式
Liquid
浓度
2.29 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Positive Samples: Rat spleen, Rat lung
Immunogen sequence: MACSIVQFCY FQDLQAARDF LFPHLREEIL SGALRRDPSK STDWEDDGWG AWEENEPQEP EEEGNTCKTQ KTSWLQDCVL SLSPTNDLMV IAREQKAVFL VPKWKYSDKG KEEMQFAVGW SGSLNVEEGE CVTSALCIPL ASQKRSSTGR PDWTCIVVGF TSGYVRFYTE NGVLLLAQLL NEDPVLQLKC RTYEIPRHPG
靶标信息
The protein encoded by this gene belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment. Mutations in this gene are associated with Martsolf syndrome.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: RAB3 GTPase activating protein subunit 2 (non-catalytic); Rab3 GTPase-activating protein 150 kDa subunit; Rab3 GTPase-activating protein non-catalytic subunit; Rab3-GAP p150; Rab3-GAP regulatory subunit; RAB3-GAP150; RGAP-iso
基因别名: KIAA0839; p150; RAB3-GAP150; RAB3GAP150; RAB3GAP2; RGD1311518; SPG69; WARBM2
UniProt ID: (Human) Q9H2M9, (Rat) Q5U1Z0
Entrez Gene ID: (Human) 25782, (Rat) 289350
intracellular protein transport
regulation of GTPase activity
positive regulation of GTPase activity
establishment of protein localization to endoplasmic reticulum membrane
positive regulation of protein lipidation
positive regulation of endoplasmic reticulum tubular network organization
positive regulation of autophagosome assembly
