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          • Primary Antibodies ›
          • RAC1/RAC2/RAC3 Antibodies

          Invitrogen

          RAC1/RAC2/RAC3 Polyclonal Antibody

          高级验证
          查看其他6个RAC1/RAC2/RAC3抗体

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          Cite RAC1/RAC2/RAC3 Polyclonal Antibody

          Additional Information:
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          • 抗体检测数据 (7)
          • 高级验证 (1)
          RAC1/RAC2/RAC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.
          RAC1/RAC2/RAC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          Group 53 Created with Sketch.

          图: 1 / 8

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          RAC1/RAC2/RAC3 Antibody (PA5-61600) in IHC (P)

          Immunohistochemical analysis of RAC1/RAC2/RAC3 in human colon using RAC1/RAC2/RAC3 Polyclonal Antibody (Product # PA5-61600) shows weak to moderate membranous/ cytoplasmic positivity in glandular cells. {{ $ctrl.currentElement.advancedVerification.fullName }} 验证信息 View more
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          RAC1/RAC2/RAC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          RAC1/RAC2/RAC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          RAC1/RAC2/RAC3 Antibody in Immunohistochemistry (Paraffin) (IHC (P))
          RAC1/RAC2/RAC3 Antibody in Immunohistochemistry (IHC)
          RAC1/RAC2/RAC3 Antibody in Western Blot (WB)
          RAC1/RAC2/RAC3 Antibody in Western Blot (WB)
          RAC1/RAC2/RAC3 Antibody in Western Blot (WB)
          RAC1/RAC2/RAC3 Antibody

          产品信息

          PA5-61600

          应用
          建议稀释比
          已发表文章

          免疫印迹 (WB)

          0.04-0.4 µg/mL
          -

          免疫组化(石蜡) (IHC (P))

          1:50-1:200
          -
          产品规格

          种属反应

          Human

          宿主/亚型

          Rabbit / IgG

          分类

          Polyclonal

          类型

          Antibody

          抗原

          Recombinant protein corresponding to Human RAC1/RAC2/RAC3

          偶联物

          Unconjugated Unconjugated Unconjugated

          形式

          Liquid

          浓度

          0.1 mg/mL

          规格

          10 µg

          纯化类型

          Antigen affinity chromatography

          保存液

          PBS, pH 7.2, with 40% glycerol

          内含物

          0.02% sodium azide

          保存条件

          Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

          运输条件

          Ambient (domestic); Wet ice (international)

          RRID

          AB_2646272

          产品详细信息

          Immunogen sequence: TKLDLRDDKD TIERLRDKKL APITYPQGLA MAREI

          Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 100%.

          靶标信息

          The protein encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.

          仅用于科研。不用于诊断过程。未经明确授权不得转售。

          篇参考文献 (0)

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          引用该产品

          生物信息学

          蛋白别名: Cell migration-inducing gene 5 protein; GX; p21-Rac1; p21-Rac2; p21-Rac3; Rac1ins; RAC2; ras-like protein; Ras-like protein TC25; ras-related C3 botulinum toxin substrate; Ras-related C3 botulinum toxin substrate 1; ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1); Ras-related C3 botulinum toxin substrate 2; ras-related C3 botulinum toxin substrate 2 (rho family, small GTP binding protein Rac2); Ras-related C3 botulinum toxin substrate 3; ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3); Ras-related C3 botulinum toxin substrate 3 (rho family, small GTP-binding protein Rac2); rho family, small GTP binding protein Rac3; Small G protein; unnamed protein product

          查看更多 收起

          基因别名: EN-7; Gx; HSPC022; IMD73A; IMD73B; IMD73C; MIG5; MRD48; p21-Rac1; p21-Rac2; Rac-1; RAC1; RAC2; RAC3; TC-25; TC25

          查看更多 收起

          UniProt ID: (Human) P63000, (Human) P15153, (Human) P60763

          查看更多 收起

          Entrez Gene ID: (Human) 5879, (Human) 5880, (Human) 5881

          查看更多 收起

          功能
          nucleotide binding GTPase activity obsolete small monomeric GTPase activity protein binding GTP binding hydrolase activity enzyme binding protein kinase binding GTP-dependent protein binding thioesterase binding macromolecular complex binding Rho GDP-dissociation inhibitor binding protein kinase regulator activity calcium-dependent protein binding
          参与通路
          actin filament organization establishment or maintenance of cell polarity small GTPase mediated signal transduction motor neuron axon guidance regulation of cell shape regulation of cell-substrate adhesion regulation of neuron maturation Wnt signaling pathway Rac protein signal transduction cerebral cortex GABAergic interneuron development regulation of cell morphogenesis cell projection assembly actin cytoskeleton organization cortical cytoskeleton organization neuron projection development regulation of actin cytoskeleton organization positive regulation of cell adhesion mediated by integrin intracellular signal transduction respiratory burst homeostasis of number of cells within a tissue neuromuscular process controlling balance neuromuscular process synaptic transmission, GABAergic cell chemotaxis postsynaptic actin cytoskeleton organization regulation of postsynapse assembly positive regulation of substrate adhesion-dependent cell spreading regulation of neutrophil migration chemotaxis signal transduction G-protein coupled receptor signaling pathway cell proliferation regulation of hydrogen peroxide metabolic process positive regulation of lamellipodium assembly regulation of T cell proliferation superoxide anion generation erythrocyte enucleation regulation of mast cell degranulation bone resorption regulation of respiratory burst regulation of mast cell chemotaxis mast cell proliferation positive regulation of mast cell proliferation lymphocyte aggregation positive regulation of neutrophil chemotaxis positive regulation of protein targeting to mitochondrion neuron migration positive regulation of protein phosphorylation auditory receptor cell morphogenesis sphingosine-1-phosphate signaling pathway epithelial cell morphogenesis endocytosis phagocytosis, engulfment inflammatory response hyperosmotic response cytoskeleton organization cell adhesion cell-matrix adhesion enzyme linked receptor protein signaling pathway axon guidance response to wounding anatomical structure morphogenesis regulation of lamellipodium assembly positive regulation of endothelial cell migration regulation of fibroblast migration negative regulation of fibroblast migration positive regulation of cell-substrate adhesion dendrite development cell migration cerebral cortex radially oriented cell migration embryonic olfactory bulb interneuron precursor migration lamellipodium assembly actin filament polymerization regulation of cell migration positive regulation of actin filament polymerization forebrain development positive regulation of microtubule polymerization ruffle organization response to lipopolysaccharide negative regulation of interleukin-23 production substrate adhesion-dependent cell spreading positive regulation of Rho protein signal transduction non-canonical Wnt signaling pathway positive regulation of insulin secretion involved in cellular response to glucose stimulus engulfment of apoptotic cell cell-cell junction organization regulation of nitric oxide biosynthetic process regulation of JAK-STAT cascade hepatocyte growth factor receptor signaling pathway regulation of neuronal synaptic plasticity negative regulation of receptor-mediated endocytosis anatomical structure arrangement neuron projection morphogenesis dendrite morphogenesis cell motility regulation of stress fiber assembly positive regulation of stress fiber assembly localization within membrane positive regulation of focal adhesion assembly positive regulation of protein kinase B signaling Wnt signaling pathway, planar cell polarity pathway positive regulation of dendritic spine development regulation of cell adhesion involved in heart morphogenesis regulation of ERK5 cascade semaphorin-plexin signaling pathway dopaminergic neuron differentiation protein localization to plasma membrane angiotensin-activated signaling pathway involved in heart process cochlea morphogenesis ruffle assembly positive regulation of ruffle assembly regulation of synaptic vesicle endocytosis positive regulation of bicellular tight junction assembly positive regulation of skeletal muscle acetylcholine-gated channel clustering interneuron migration midbrain dopaminergic neuron differentiation positive regulation of ovarian follicle development regulation of neuron migration
          It has to be done as per old AB suggested Products section.

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