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Invitrogen
RACK1 Polyclonal Antibody
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产品信息
PA5-80964
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant Human RACK1/GNB2L1 Protein (Met1-Arg317)
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A, Antigen affinity chromatography
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This product is preservative free. It is recommended to add sodium azide to avoid contamination (final concentration 0.05%-0.1%).
This antibody has specificity for Human RACK1/GNB2L1.
靶标信息
RACK1 (receptor for activated C kinase 1) was identified through its binding to various PKC isoforms. Its main function is to recruit PKC and various other proteins to specific locations to form multiprotein complexes, mediating various signal pathways. RACK1 is required for VANGL2 membrane localization and for PTK2/FAK1 phosphorylation and dephosphorylation.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cell proliferation-inducing gene 21 protein; guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1; guanine nucleotide binding protein beta polypeptide 2-like 1; Guanine nucleotide-binding protein subunit beta-2-like 1; Guanine nucleotide-binding protein subunit beta-like protein 12.3; HLC-7; Human lung cancer oncogene 7 protein; lung cancer oncogene 7; OTTHUMP00000223870; OTTHUMP00000223891; OTTHUMP00000223893; OTTHUMP00000223900; OTTHUMP00000223901; OTTHUMP00000223902; OTTHUMP00000223930; OTTHUMP00000223931; proliferation-inducing gene 21; protein homologous to chicken B complex protein, guanine nucleotide binding; rack-1; Receptor for activated C kinase; Receptor of activated protein C kinase 1; receptor of activated protein kinase C 1; Small ribosomal subunit protein RACK1
基因别名: Gnb2-rs1; GNB2L1; H12.3; HLC-7; HLC7; PIG21; RACK1
UniProt ID: (Human) P63244
Entrez Gene ID: (Human) 10399
protein kinase C binding
receptor binding
protein binding
ion channel inhibitor activity
cysteine-type endopeptidase activator activity involved in apoptotic process
enzyme binding
protein phosphatase binding
protein tyrosine kinase inhibitor activity
receptor tyrosine kinase binding
protein complex scaffold
signaling adaptor activity
SH2 domain binding
protein homodimerization activity
poly(A) RNA binding
cadherin binding involved in cell-cell adhesion
osteoblast differentiation
positive regulation of protein phosphorylation
apoptotic process
activation of cysteine-type endopeptidase activity involved in apoptotic process
cell cycle
gastrulation
negative regulation of gene expression
regulation of tumor necrosis factor-mediated signaling pathway
viral process
negative regulation of translation
negative regulation of Wnt signaling pathway
negative regulation of cell growth
positive regulation of cell migration
positive regulation of cAMP catabolic process
positive regulation of proteasomal ubiquitin-dependent protein catabolic process
positive regulation of protein homooligomerization
regulation of protein localization
negative regulation of peptidyl-serine phosphorylation
positive regulation of Golgi to plasma membrane protein transport
positive regulation of apoptotic process
positive regulation of GTPase activity
rhythmic process
negative regulation of phagocytosis
regulation of cell division
positive regulation of cyclic-nucleotide phosphodiesterase activity
regulation of cell cycle
negative regulation of protein kinase B signaling
positive regulation of mitochondrial depolarization
negative regulation of protein tyrosine kinase activity
cellular response to glucose stimulus
cellular response to growth factor stimulus
cell-cell adhesion
negative regulation of endoplasmic reticulum unfolded protein response
negative regulation of hydrogen peroxide-induced neuron death
regulation of establishment of cell polarity
positive regulation of ceramide biosynthetic process
positive regulation of gastrulation
positive regulation of intrinsic apoptotic signaling pathway
