Search
Disclaimer
Clicking the images or links will redirect you to a website hosted by BenchSci that provides third-party scientific content. Neither the content nor the BenchSci technology and processes for selection have been evaluated by us; we are providing them as-is and without warranty of any kind, including for use or application of the Thermo Fisher Scientific products presented.
Invitrogen
RAD51 Recombinant Rabbit Monoclonal Antibody (HL3807)
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promotions']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.viewpromo']}}
{{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.promocode']}}: {{promo.promoCode}} {{promo.promoTitle}} {{promo.promoDescription}}. {{$productOrderCtrl.translations['antibody.pdp.commerceCard.promotion.learnmore']}}
Additional Information:
{{banner.description}}
产品信息
MA568319
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
HL3807
抗原
Recombinant fragment of human Rad51.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Protein A
保存液
PBS
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
RAD51 plays a critical role in homologous strand exchange, a key step in DNA repair through homologous recobination. It binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. RAD51 catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. It binds to a single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Mutations in the gene can results in breast cancer, mirror movements 2 and fanconi anemia.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
篇参考文献 (0)
您是否在文献中引用过该产品？请点击下方按钮邮件告知我们。
生物信息学
蛋白别名: DNA repair protein RAD51 homolog 1; RAD51 homolog A
基因别名: AV304093; Rad51; Rad51a; Reca
UniProt ID: (Mouse) Q08297
Entrez Gene ID: (Mouse) 19361
nucleotide binding
DNA binding
chromatin binding
damaged DNA binding
double-stranded DNA binding
single-stranded DNA binding
protein binding
ATP binding
protein C-terminus binding
DNA-dependent ATPase activity
identical protein binding
single-stranded DNA-dependent ATPase activity
DNA polymerase binding
DNA metabolism protein
double-strand break repair via homologous recombination
regulation of protein phosphorylation
DNA metabolic process
DNA unwinding involved in DNA replication
DNA repair
DNA recombination
cellular response to DNA damage stimulus
meiotic nuclear division
reciprocal meiotic recombination
regulation of double-strand break repair via homologous recombination
replication fork processing
telomere organization
positive regulation of DNA ligation
protein homooligomerization
chromosome organization involved in meiotic cell cycle
cellular response to alkaloid
cellular response to ionizing radiation
cellular response to hydroxyurea
cellular response to camptothecin
replication-born double-strand break repair via sister chromatid exchange
