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Invitrogen
RAD51B Polyclonal Antibody
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RAD51B Antibody (PA5-93318) in WB
Western blot analysis of RAD51B in extracts of various cell lines. Samples were incubated with RAD51B Polyclonal antibody (Product # PA5-93318) using a dilution of 1:1,000, followed by HRP Goat Anti-Rabbit IgG (H+L) at a dilution of 1:10,000. Lysates/proteins: 25 µg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 90s.
产品信息
PA5-93318
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant fusion protein containing a sequence corresponding to amino acids 1-384 of human RAD51B (NP_5981932)
偶联物
形式
Liquid
浓度
0.47 mg/mL
纯化类型
Affinity Chromatography
保存液
PBS, pH 7.3, with 50% glycerol
内含物
0.01% thimerosal
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: MGSKKLKRVG LSQELCDRLS RHQILTCQDF LCLSPLELMK VTGLSYRGVH ELLCMVSRAC APKMQTAYGI KAQRSADFSP AFLSTTLSAL DEALHGGVAC GSLTEITGPP GCGKTQFCIM MSILATLPTN MGGLEGAVVY IDTESAFSAE RLVEIAESRF PRYFNTEEKL LLTSSKVHLY RELTCDEVLQ RIESLEEEII SKGIKLVILD SVASVVRKEF DAQLQGNLKE RNKFLAREAS SLKYLAEEFS IPVILTNQIT THLSGALASQ ADLVSPADDL SLSEGTSGSS CVIAALGNTW SHSVNTRLIL QYLDSERRQI LIAKSPLAPF TSFVYTIKEE GLVLQETTFC SVTQAELNWA PEILPPQPPE QLGLQMCHHT QLIF; Positive Samples: Mouse kidney, Rat kidney; Cellular Location: Nucleus
靶标信息
Five human RAD 51 homologues have been identified: XRCC2, XRCC3, RAD51B, RAD51C, and RAD51D. Each of these homologues interacts with one or more of the others, with all of the proteins involved in one complex or multiple smaller complexes. Rad51B plays a role in meiotic recombination and/or recombinational repair.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DNA repair protein RAD51 homolog 2; hREC2; MGC34245; R51H2; R51H2REC2hREC2; RAD51 homolog B; RAD51 paralog B; RAD51-like 1; RAD51-like protein 1
基因别名: AI553500; mREC2; R51H2; Rad51b; Rad51l1; Rec2; RGD1560681
UniProt ID: (Mouse) O35719
Entrez Gene ID: (Mouse) 19363, (Rat) 500679
double-strand break repair via homologous recombination
in utero embryonic development
blastocyst growth
DNA repair
DNA recombination
cellular response to DNA damage stimulus
positive regulation of cell proliferation
positive regulation of G2/M transition of mitotic cell cycle
somite development
DNA metabolic process
biological_process
