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Invitrogen
RAG1 Polyclonal Antibody
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产品信息
PA5-69206
产品规格
种属反应
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
synthetic peptide corresponding to a region of mouse RAG1
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
This target displays homology in the following species: Horse: 100%; Mouse: 100%; Pig: 100%; Rat: 100%
靶标信息
The protein encoded by this gene is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires RAG2. Defects in this gene can be the cause of several diseases.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: MGC43321; RAG-1; RAG-1 Antibody; recombinase activating gene 1; recombination activating gene 1 Antibody; recombination activating protein 1; recombination-activating gene 1; RNF74 Antibody; V(D)J recombination-activating protein 1
基因别名: Rag-1; Rag1
UniProt ID: (Mouse) P15919
Entrez Gene ID: (Mouse) 19373
nucleic acid binding
DNA binding
catalytic activity
nuclease activity
endonuclease activity
ubiquitin-protein transferase activity
protein binding
zinc ion binding
UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity
hydrolase activity
hydrolase activity, acting on ester bonds
ligase activity
acid-amino acid ligase activity
ribosomal S6-glutamic acid ligase activity
histone binding
phosphoric ester hydrolase activity
protein homodimerization activity
sequence-specific DNA binding
T/G mismatch-specific endonuclease activity
coenzyme F420-0 gamma-glutamyl ligase activity
coenzyme F420-2 alpha-glutamyl ligase activity
retroviral 3' processing activity
metal ion binding
ubiquitin protein ligase activity
protein-glycine ligase activity
protein-glycine ligase activity, initiating
protein-glycine ligase activity, elongating
tubulin-glycine ligase activity
protein-glutamic acid ligase activity
tubulin-glutamic acid ligase activity
DNA metabolism protein
endodeoxyribonuclease
nucleic acid metabolism protein
adaptive immune response
pre-B cell allelic exclusion
DNA recombination
metabolic process
histone monoubiquitination
obsolete death
chromatin modification
B cell differentiation
T cell differentiation in thymus
V(D)J recombination
T cell homeostasis
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
regulation of T cell differentiation
thymus development
protein autoubiquitination
negative regulation of T cell apoptotic process
negative regulation of thymocyte apoptotic process
nucleic acid phosphodiester bond hydrolysis
