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This antibody is predicted to react with human and mouse based on sequence homology.
This antibody is tested in Peptide ELISA: antibody detection limit dilution 64,000.
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: MGC38240; receptor (calcitonin) activity modifying protein 1; Receptor activity-modifying protein 1
基因别名: Ramp1
UniProt ID: (Rat) Q9JJ74
Entrez Gene ID: (Rat) 58965