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Alomone Labs, LTD
RAMP1 (extracellular) Polyclonal Antibody
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RAMP1 (extracellular) Antibody (ARR-021-200UL) in ICC/IF
Expression of RAMP1 in rat PC12 cells - Cell surface detection of RAMP1 in intact living rat pheochromocytoma (PC12) cells. A. Extracellular staining of cells using Anti-RAMP1 (extracellular) Antibody (#ARR-021), (1:50), (red). B. Live view of cells.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
ARR-021-200UL
应用
建议稀释比
已发表文章
产品规格
种属反应
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
CRDPDYGTLIQE, corresponding to amino acid residues 27-38 of rat RAMP1, Extracellular, N-terminus
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Lyophilized
浓度
0.85 mg/mL
规格
170 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4, with 1% BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Reconstitution: 25 µL, 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
The protein encoded by this gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP1) protein, CRLR functions as a CGRP receptor. The RAMP1 protein is involved in the terminal glycosylation, maturation, and presentation of the CGRP receptor to the cell surface.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: membrane protein; RAMP1; MGC38240; RAMP1; receptor (calcitonin) activity modifying protein 1; receptor (G protein-coupled) activity modifying protein 1; unnamed protein product
基因别名: 9130218E19Rik
UniProt ID: (Rat) Q9JJ74, (Mouse) Q9WTJ5
Entrez Gene ID: (Rat) 58965, (Mouse) 51801
angiogenesis
calcium ion transport
intracellular protein transport
G-protein coupled receptor signaling pathway
adenylate cyclase-activating G-protein coupled receptor signaling pathway
regulation of G-protein coupled receptor protein signaling pathway
positive regulation of glycoprotein biosynthetic process
protein transport
receptor internalization
cellular response to hormone stimulus
protein localization to plasma membrane
amylin receptor signaling pathway
amylin receptor 1 signaling pathway
calcitonin gene-related peptide receptor signaling pathway
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