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Invitrogen
RANBP3 Polyclonal Antibody
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产品信息
PA1-084
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Rat
已发表种属
Dog,
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Synthetic peptide corresponding to residues M(1) A D L A N E E K P A L A(13) C of human RanBP3.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 1mg/mL BSA
内含物
0.05% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
PA1-084 detects Ran binding protein 3 (RanBP3) from human and rat cells.
PA1-084 has been successfully used in Western blot and immunofluorescence procedures. By Western blot this antibody detects an ~60 kDa protein representing RanBP3 from HeLa cell extracts. Immunofluorescence staining of RanBP3 in NRK cells with PA1-084 results in diffuse nuclear staining.
The PA1-084 immunogen is a synthetic peptide corresponding to residues M(1) A D L A N E E K P A L A(13) C of human RanBP3. The PA1-084 immunizing peptide (Cat. # PEP-177) is available for use in neutralization and control experiments.
靶标信息
Ran binding protein 3 (RanBP3) is a member of Ran GTPase binding proteins that is located at the nuclear pore complex (NPC) and plays an essential role in the transport between cytoplasm and nucleus. RANPB3 is expessed as two spliced forms, RanBP3a and RanBP3b, both of which contains two FXFG motifs, characteristic of a subgroup of nucleoporins in addition to nuclear localization signal in the amino-terminal region (amino acid residues 40-57) and a unique acidic carboxyl terminus which is integral to its switch function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: RAN binding protein 3; Ran-binding protein 3; RAN-binding protein-3; RANB3; RanBP3
基因别名: RANBP3
UniProt ID: (Human) Q9H6Z4
Entrez Gene ID: (Human) 8498, (Rat) 501281
