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Ran binding protein 3 (RanBP3) is a member of Ran GTPase binding proteins that is located at the nuclear pore complex (NPC) and plays an essential role in the transport between cytoplasm and nucleus. RANPB3 is expessed as two spliced forms, RanBP3a and RanBP3b, both of which contains two FXFG motifs, characteristic of a subgroup of nucleoporins in addition to nuclear localization signal in the amino-terminal region (amino acid residues 40-57) and a unique acidic carboxyl terminus which is integral to its switch function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Ran-binding protein 3; RAN-binding protein-3; RANB3; RanBP3
基因别名: RANBP3
UniProt ID: (Human) O75759
Entrez Gene ID: (Human) 8498
分子生物学功能: scaffold/adaptor protein