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Invitrogen
RAP2A/RAP2B Monoclonal Antibody (455410)
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产品信息
MA5-61476
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Mouse
/ IgG2b
分类
Monoclonal
类型
Antibody
克隆号
455410
抗原
E. coli-derived recombinant human Rap2A/B, Met1-Gln183
偶联物
形式
Lyophilized
浓度
0.5 mg/mL
纯化类型
Protein A/G
保存液
PBS with trehalose
内含物
no preservative
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute at 0.5 mg/mL in sterile PBS.
靶标信息
RAP2A and RAP2B are genes encoding small GTPases that belong to the Ras-related protein family. These proteins are involved in various cellular processes, including cell proliferation, differentiation, and migration. RAP2A and RAP2B function as molecular switches, cycling between an active GTP-bound state and an inactive GDP-bound state, thereby regulating signal transduction pathways. They play crucial roles in the organization of the actin cytoskeleton, vesicle trafficking, and cell adhesion. RAP2A and RAP2B are implicated in the regulation of neuronal development and plasticity, and their dysregulation has been associated with neurological disorders. Additionally, abnormal expression or mutations in these genes have been linked to cancer progression, as they can influence tumor cell migration and invasion. Understanding the specific mechanisms and functions of RAP2A and RAP2B is important for elucidating their roles in both normal cellular physiology and disease states. As such, these genes are significant targets in research aimed at developing therapeutic interventions for cancer, neurodegenerative diseases, and other conditions involving cellular signaling abnormalities.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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