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Invitrogen
RAPGEF4 Polyclonal Antibody
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产品信息
PA5-56019
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: VIYGKGVVCT LHEGDDFGKL ALVNDAPRAA SIVLREDNCH FLRVDKEDFN RILRDVEANT VRLKEHDQDV LVLEKVPAGN RASNQGNSQP QQKYTVMSGT PEKILEHFLE TIRLEATLNE ATDSVLNDFI MMHCVFMPNT QLC
Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 98%.
靶标信息
Guanine nucleotide exchange factor (GEF) for RAP1A, RAP1B and RAP2A small GTPases that is activated by binding cAMP. Seems not to activate RAB3A. Involved in cAMP-dependent, PKA-independent exocytosis through interaction with RIMS2.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cAMP-GEFII; cAMP-regulated guanine nucleotide exchange factor II; EPAC 2; Exchange factor directly activated by cAMP 2; Exchange protein directly activated by cAMP 2; gefii; putative protein product of Nbla00496; Rap guanine nucleotide exchange factor (GEF) 4; Rap guanine nucleotide exchange factor 4; RAP guanine-nucleotide-exchange factor (GEF) 4
基因别名: CAMP-GEFII; CGEF2; EPAC; EPAC 2; EPAC2; Nbla00496; RAPGEF4
UniProt ID: (Human) Q8WZA2
Entrez Gene ID: (Human) 11069
