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This Antibody was verified by Cell treatment to ensure that the antibody binds to the antigen stated.
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This antibody is predicted to react with canine, guinea pig, mouse and non-human primate based on 100% sequence homology.
This antibody is specific for the ~48 kDa RXR-b protein.
Retinoic Acid (RA; active metabolite of vitamin A) plays a prominent role in regulating the transition of proliferating precursor cells (such as carcinoma cells and neuronal precursors) to postmitotic differentiated cells. The Retinoid X Receptors (RXRs) family (RXR alpha, beta, and gamma), preferentially bind 9-cis -RA and regulate gene transcription by forming heterodimers with a second family of RA receptors. RAs have been suggested to potentially play a therapeutic role in cervical cancer. RAs are known to play key roles in neuronal development and an increasing body of evidence indicates that retinoid signaling may regulate synaptic plasticity and associated learning and memory behaviors.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HBV-activated protein; hepatitis B virus activated protein; Nuclear receptor subfamily 1 group B member 2; RAR beta; RAR-b; RAR-beta; RAR-Beta2; RAR-Beta4; RAR-epsilon; retinoic acid; retinoic acid receptor; Retinoic acid receptor beta; retinoic acid receptor, beta polypeptide
基因别名: HAP; MCOPS12; NR1B2; RARB; RARbeta1; RRB2
UniProt ID: (Human) P10826
Entrez Gene ID: (Human) 5915, (Rat) 24706
分子生物学功能: C4 zinc finger nuclear receptor