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Abnova
RARRES2 Polyclonal Antibody, MaxPab™
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RARRES2 Antibody (H00005919-D01P) in WB
Western Blot analysis of RARRES2 expression in transfected 293T cell line (H00005919-T01) by RARRES2 MaxPab polyclonal antibody.
Lane 1: RARRES2 transfected lysate(18.60 KDa).
Lane 2: Non-transfected lysate.
Lane 1: RARRES2 transfected lysate(18.60 KDa).
Lane 2: Non-transfected lysate.
产品信息
H00005919-D01P
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
RARRES2 (NP_002880.1, 1 a.a. approximately 163 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
See Label
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Sequence of this protein is as follows: MRRLLIPLAL WLGAVGVGVA ELTEAQRRGL QVALEEFHKH PPVQWAFQET SVESAVDTPF PAGIFVRLEF KLQQTSCRKR DWKKPECKVR PNGRKRKCLA CIKLGSEDKV LGRLVHCPIE TQVLREAEEH QETQCLRVQR AGEDPHSFYF PGQFAFSKAL PRS
靶标信息
Retinoids act through ligand-dependent transcription factors, retinoid X receptor (RXRs) and retinoic acid receptors (RARs). Tazarotene-induced gene (TIG) proteins, also designated retinoic acid receptor responder proteins or RAR-responsive proteins, can be membrane bound or secreted. TIGs act as tumor suppressor genes in human cancers and are highly expressed in skin, hair follicles and endothelial cells as well as in pancreas, spleen and intestine. TIGs are activated by tazarotene and have been implicated as growth regulators that mediate the growth suppressive effects of retinoids. TIG2 is a secreted protein that is mainly expressed in epidermis, hair follicles and endothelial cells. TIG2 is inhibited in psoriatic lesions and is activated by tazarotene in skin rafts and in epidermis of psoriatic lesions.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Chemerin; RAR-responsive protein TIG2; retinoic acid receptor responder (tazarotene induced) 2; Retinoic acid receptor responder protein 2; Tazarotene-induced gene 2 protein; TIG-2; TIG2HP10433
基因别名: 0610007L05Rik; AI303516; HP10433; RARRES2; TIG2
UniProt ID: (Human) Q99969, (Mouse) Q9DD06
Entrez Gene ID: (Human) 5919, (Mouse) 71660
retinoid metabolic process
positive regulation of protein phosphorylation
chemotaxis
defense response
inflammatory response
positive regulation of macrophage chemotaxis
cell differentiation
positive regulation of fat cell differentiation
embryonic digestive tract development
brown fat cell differentiation
positive regulation of chemotaxis
regulation of lipid catabolic process
positive regulation of glucose import in response to insulin stimulus
in utero embryonic development
platelet degranulation
