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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Product may be used with Western Blot (Transfected lysate).
Immunogen sequence: GYHSDGDYGE HDYRHDISDE RESKTIMLRG LPITITESDI REMMESFEGP QPADVRLMKR KTGVSRGFAF VEFYHLQDAT SWMEANQKKL VIQGKHIAMH YSNPRPKFED
DEF-3 and LUCA15 belong to an evolutionarily conserved family of RNA binding proteins and share similar expression patterns. Both DEF-3 and LUCA15 are highly expressed in adult heart and thymus as well as fetal kidney. Conversely, fetal thymus and adult kidney express very little DEF-3 and LUCA15. In the haemopoietic system of mice, the expression of DEF-3 is downregulated upon differentiation of progenitor cells into granulocytes but persists during macrophage development. Both DEF-3 and LUCA15 contain two zinc finger motifs, a bipartite nuclear signal and two RNA binding motifs. DEF-3 and LUCA15 are capable of specifically binding poly(G) RNA.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: putative tumor suppressor; putative tumor suppressor LUCA15; renal carcinoma antigen NY-REN-9; unnamed protein product
基因别名: G15; H37; LUCA-15; LUCA15; RMB5
UniProt ID: (Human) P52756
Entrez Gene ID: (Human) 10181