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Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human U2OS whole cell, human PC-3 whole cell, human U-87MG whole cell, human A549 whole cell, human Hela whole cell, rat heart tissue, mouse testicular tissue. IHC: human oesophagus squama cancer tissue, mouse brain tissue, rat brain tissue. ICC/IF: U20S cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
This gene encodes an RNA-binding protein that belongs to the c-myc gene single-strand binding protein family. These proteins are characterized by the presence of two sets of ribonucleoprotein consensus sequence (RNP-CS) that contain conserved motifs, RNP1 and RNP2, originally described in RNA binding proteins, and required for DNA binding. These proteins have been implicated in such diverse functions as DNA replication, gene transcription, cell cycle progression and apoptosis. The encoded protein was isolated by virtue of its binding to an upstream element of the alpha2(I) collagen promoter. The observation that this protein localizes mostly in the cytoplasm suggests that it may be involved in a cytoplasmic function such as controlling RNA metabolism, rather than transcription. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: RNA binding motif, single stranded interacting protein 3; RNA-binding motif, single-stranded-interacting protein 3; RNA-binding protein; RNA-binding protein RBMS3
基因别名: 6720477E09Rik; 8430436O14Rik; RBMS3
UniProt ID: (Human) Q6XE24, (Mouse) Q8BWL5
Entrez Gene ID: (Human) 27303, (Mouse) 207181, (Rat) 680726