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RBPJ Polyclonal Antibody

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查看其他13个RBPJ抗体

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RBPJ Polyclonal Antibody

产品信息

720219

应用
建议稀释比
已发表文章

免疫印迹 (WB)

1-2 µg/mL
-

免疫细胞化学 (ICC/IF)

2 µg/mL
-

染色质免疫沉淀 实验 (ChIP)

1.5 µg x 10^6 cells
-
产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Protein corresponding to Human RBPJ (aa 1-200)
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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.5 mg/mL

规格

100 µg

纯化类型

Affinity chromatography

保存液

PBS, pH 7.4, with 0.1% BSA, 30% glycerol

内含物

0.09% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

RRID

AB_2633205

产品详细信息

These Polyclonal antibodies are of rabbit origin developed by immunizing animals with proteins or peptides. The polyclonal antibody is purified by affinity purification from the rabbit sera generated after immunizing the rabbits with a specific type of protein or peptide. The purified antibody is tested for its functionality in various relevant research applications. The antibody is developed for Research Use Only and is non-hazardous or non-infectious in nature.

This antibody is predicted to react with Mouse, Monkey, Bovine, Equine and Pig

靶标信息

CSL plays a role in the regulatory network through which muscle cells coordinate their structural and functional states during growth, adaptation, and repair. The protein is abundantly expressed in heart and skeletal muscle and expression is increased by passive stretch. Mutations in this gene can lead to X-linked deafness.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: CBF-1; CSL family DNA binding factor 1; H-2K binding factor-2; immunoglobulin kappa J region recombination signal binding protein 1; J kappa-recombination signal-binding protein; RBP-J; RBP-J kappa; rbp-jkappa; Recombining binding protein suppressor of hairless; Renal carcinoma antigen NY-REN-30; suppressor of hairless homolog; unnamed protein product

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基因别名: AOS3; CBF-1; CBF1; csl; IGKJRB; IGKJRB1; KBF2; RBP-J; RBP-J kappa; RBP-JK; RBPJ; RBPJK; RBPSUH; SUH

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UniProt ID: (Human) Q06330

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Entrez Gene ID: (Human) 3516

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功能
RNA polymerase II core promoter proximal region sequence-specific DNA binding RNA polymerase II transcription factor activity, sequence-specific DNA binding transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding DNA binding chromatin binding transcription factor activity, sequence-specific DNA binding protein binding sequence-specific DNA binding RNA polymerase II sequence-specific DNA binding transcription factor binding DNA-binding transcription factor binding
参与通路
negative regulation of transcription from RNA polymerase II promoter angiogenesis somitogenesis epithelial to mesenchymal transition blood vessel remodeling inflammatory response to antigenic stimulus secondary heart field specification outflow tract morphogenesis endocardium development endocardium morphogenesis aortic valve development pulmonary valve development epithelial to mesenchymal transition involved in endocardial cushion formation cardiac left ventricle morphogenesis ventricular trabecula myocardium morphogenesis regulation of transcription, DNA-templated regulation of transcription from RNA polymerase II promoter humoral immune response Notch signaling pathway positive regulation of transcription of Notch receptor target heart development cell proliferation auditory receptor cell fate commitment epidermal cell fate specification regulation of gene expression positive regulation of gene expression pituitary gland development hemopoiesis cell differentiation neuron differentiation B cell differentiation keratinocyte differentiation negative regulation of ossification positive regulation of BMP signaling pathway somatic stem cell population maintenance dorsal aorta morphogenesis atrioventricular canal development defense response to bacterium myeloid dendritic cell differentiation regulation of generation of precursor metabolites and energy cell fate commitment negative regulation of cell differentiation negative regulation of transcription, DNA-templated positive regulation of transcription from RNA polymerase II promoter regulation of timing of cell differentiation animal organ development sebaceous gland development hair follicle maturation artery morphogenesis epithelial cell proliferation regulation of epithelial cell proliferation positive regulation of epithelial cell proliferation positive regulation of cardiac muscle cell proliferation cardiac muscle cell myoblast differentiation ventricular septum morphogenesis Clara cell differentiation labyrinthine layer blood vessel development arterial endothelial cell fate commitment regulation of cell adhesion involved in heart morphogenesis stem cell proliferation blood vessel lumenization positive regulation of canonical Wnt signaling pathway blood vessel endothelial cell fate specification negative regulation of cold-induced thermogenesis positive regulation of ERBB signaling pathway positive regulation of ephrin receptor signaling pathway positive regulation of cell proliferation involved in heart morphogenesis negative regulation of stem cell proliferation
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