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Agrisera
RCD1/Radical cell death 1 Polyclonal Antibody
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RCD1/Radical cell death 1 Antibody (AS12-2602) in WB
5 mg of total protein from Arabidopsis thaliana seedlings expressing RCD 1-HA under native promoter extracted with RIPA buffer for protein extraction (50 m M Tris-HCl p H 7,5,150 m M Na Cl, 1% Triton X-100,0.5% sodium deoxycholate, protease inhibitor cocktail 1:100 50 µm MG 132) were used for immunoprecipitation and afterwards separated on 10% SDS-PAGE and blotted 1 h to PVDF using tank transfer. Blots were... View More
产品信息
AS12-2602
产品规格
种属反应
Plant
宿主/亚型
Rabbit
分类
Polyclonal
类型
Antibody
抗原
KLH-conjugated synthetic peptide derived from Arabidopsis thaliana RCD1 protein sequence.
偶联物
形式
Lyophilized
规格
100 µg
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Store lyophilized/reconstituted at -20°C; once reconstituted make aliquots to avoid repeated freeze-thaw cycles. Please remember to spin the tubes briefly prior to opening them to avoid any losses that might occur from material adhering to the cap or sides of the tube.
For reconstitution add 50 µL of sterile water.
Specific Species Reactivity: Arabidopsis thaliana
靶标信息
RCD1 encodes a nuclear protein that functions as an interaction hub integrating environmental and hormonal cues into transcriptional regulation. In Arabidopsis, RCD1 localizes predominantly to the nucleus and is built around an N-terminal WWE protein-protein interaction domain together with a central region resembling the core catalytic fold of poly(ADP-ribose) polymerases (PARP-like) and a conserved C-terminal region; consistent with this modular architecture, RCD1 binds numerous transcription factors from multiple families and engages many partners through short linear motifs within intrinsically disordered regions of those transcription factors. Functionally, genetic and physiological studies support that RCD1 modulates stress and development, including responses to reactive oxygen species and hormone signaling, and it can restrain specific NAC transcription factors (e.g., ANAC013/ANAC017) that mediate mitochondrial retrograde signaling, thereby coordinating chloroplast and mitochondrial redox-associated pathways and shaping the expression of stress-responsive nuclear genes.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ARABIDOPSIS THALIANA P8 (INTERACTING PROTEIN); AT1G32230; ATP8; AtRCD1; CEO; CEO1; F3C3.1; F3C3_1; RADICAL-INDUCED CELL DEATH1; REDOX IMBALANCED 1; RIMB1
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