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Invitrogen
REPIN1 Polyclonal Antibody
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产品信息
PA5-31367
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Recombinant protein encompassing a sequence within the center region of human REPIN1. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.74 mg/mL
纯化类型
Antigen affinity chromatography
保存液
0.1M tris glycine, pH 7, with 20% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: HeLa.
Predicted reactivity: Mouse (96%), Rat (97%), Bovine (98%).
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
Replication initiator 1 (REPIN1) is a gene encoding a zinc-finger protein that plays a critical role in various metabolic processes. Located on chromosome 7 in humans, REPIN1 is prominently expressed in liver and adipose tissues. It is associated with the regulation of body weight and triglyceride levels, as evidenced by its locus within a quantitative trait locus (QTL) related to these metabolic traits. The REPIN1 protein is involved in enhancing DNA bending, which is crucial for replication initiation. Studies have shown that deleting REPIN1 in the liver can lead to improved insulin sensitivity and altered lipid metabolism, with secondary effects on adipose tissue. Additionally, REPIN1 is implicated in iron metabolism and apoptosis regulation, further underscoring its multifaceted role in cellular processes.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 60 kDa origin-specific DNA-binding protein; 60 kDa replication initiation region protein; ATT-binding protein; DHFR oribeta-binding protein RIP60; DNA-binding protein REPIN1; H_DJ0584D14.12; replication initiation region protein (60kD); Zinc finger protein 464; zinc finger protein 464 (RIP60); zinc finger protein AP4
基因别名: AP4; REPIN1; RIP60; Zfp464; ZNF464
UniProt ID: (Human) Q9BWE0
Entrez Gene ID: (Human) 29803
