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Invitrogen
REV3L Polyclonal Antibody
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REV3L Antibody (PA5-104483) in IHC (P)
Immunohistochemistry analysis of paraffin-embedded REV3L in human liver tissue sections. Antigen retrieval was performed using citrate buffer. Samples were blocked with blocking buffer (1.5 hr, 22°C), incubated with REV3L polyclonal antibody (Product # PA5-104483) using a dilution of 1:100 (1.5 hr, 22°C), followed by HRP conjugated goat anti-rabbit.
产品信息
PA5-104483
产品规格
种属反应
Human,
Mouse
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human REV3L(Accession O60673), corresponding to amino acid residues V238-D288.
偶联物
形式
Liquid
浓度
1 mg/mL
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total REV3L.
靶标信息
Catalytic subunit of the DNA polymerase zeta complex, an error-prone polymerase specialized in translesion DNA synthesis (TLS). Lacks an intrinsic 3'-5' exonuclease activity and thus has no proofreading function.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DNA polymerase zeta catalytic subunit; Protein reversionless 3-like; Rev-3, yeast, homolog-like (polymerase, DNA, zeta); REV3-like; REV3-like, polymerase (DNA directed), zeta, catalytic subunit; Seizure-related protein 4
基因别名: POLZ; Rev; REV3; REV3L; Sez4
UniProt ID: (Human) O60673, (Mouse) Q61493
Entrez Gene ID: (Human) 5980, (Mouse) 19714
nucleotide binding
DNA binding
DNA-directed DNA polymerase activity
protein binding
3'-5' exonuclease activity
metal ion binding
4 iron, 4 sulfur cluster binding
nucleic acid binding
transferase activity
nucleotidyltransferase activity
iron-sulfur cluster binding
DNA metabolism protein
DNA-directed DNA polymerase
nucleic acid metabolism protein
