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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: MKVKDLRDYL SLHDISTEMC REKEELVLLV LGQQPVISQE DRTRASTLSP DFPEQQAFLT QPHSSMVPPT SPNLPSSS
Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 86%.
Has E3 ubiquitin protein ligase activity. Regulates the levels of CASP8 and CASP10 by targeting them for proteasomal degradation. Has anti-apoptotic activity. May bind phosphatidylinositol phosphates.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: CARP-2; Caspase regulator CARP2; Caspases-8 and -10-associated RING finger protein 2; E3 ubiquitin-protein ligase rififylin; Fring; FYVE-RING finger protein Sakura; RING finger and FYVE-like domain-containing protein 1; RING finger protein 189; RING finger protein 34-like; RING-type E3 ubiquitin transferase rififylin
基因别名: RFFL; RNF189; RNF34L
Entrez Gene ID: (Human) 117584