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Recommended positive controls: 293T transfected recombinant RGS17.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: Regulator of G-protein signaling 17; RGS17
基因别名: hRGS17; RGS-17; RGS17; RGSZ2
UniProt ID: (Human) Q9UGC6
Entrez Gene ID: (Human) 26575