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Abnova
RGS2 Polyclonal Antibody, MaxPab™
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产品信息
H00005997-B01P
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG
分类
Polyclonal
类型
Antibody
抗原
RGS2 (NP_002914.1, 1 a.a. approximately 211 a.a) full-length human protein.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Transfected lysate).
The Isotype of this product is composed of an IgG Mixture.
Immunogen sequence: MQSAMFLAVQ HDCRPMDKSA GSGHKSEEKR EKMKRTLLKD WKTRLSYFLQ NSSTPGKPKT GKKSKQQAFI KPSPEEAQLW SEAFDELLAS KYGLAAFRAF LKSEFCEENI EFWLACEDFK KTKSPQKLSS KARKIYTDFI EKEAPKEINI DFQTKTLIAQ NIQEATSGCF TTAQKRVYSL MENNSYPRFL ESEFYQDLCK KPQITTEPHA T
靶标信息
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: Cell growth-inhibiting gene 31 protein; cell growth-inhibiting protein 31; G0 to G1 switch regulatory 8, 24kD; G0/G1 switch regulatory protein 8; Regulator of G-protein signaling 2; regulator of G-protein signaling 2, 24kDa; RGS2
基因别名: G0S8; GIG31; RGS2
UniProt ID: (Human) P41220
Entrez Gene ID: (Human) 5997
regulation of translation
cell cycle
spermatogenesis
regulation of G-protein coupled receptor protein signaling pathway
negative regulation of phospholipase activity
negative regulation of cardiac muscle hypertrophy
positive regulation of microtubule polymerization
negative regulation of MAP kinase activity
positive regulation of GTPase activity
negative regulation of cAMP-mediated signaling
negative regulation of G-protein coupled receptor protein signaling pathway
brown fat cell differentiation
relaxation of cardiac muscle
relaxation of vascular smooth muscle
positive regulation of cardiac muscle contraction
regulation of adrenergic receptor signaling pathway
