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Invitrogen
RGS2 Polyclonal Antibody
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图: 1 / 3
RGS2 Antibody (PA5-102486) in ICC/IF
Immunofluorescent analysis of RGS2 in HepG2. Samples were fixed with paraformaldehyde, permeabilized with 0.1% Triton X-100, blocked with 10% serum (45 min at 25°C) incubated with RGS2 polyclonal antibody (Product # PA5-102486) using a dilution of 1:200 (1 hr, 37°C), and followed by goat anti-rabbit IgG Alexa Fluor 594 at a dilution of 1:600.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5-102486
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthesized peptide derived from human RGS2(Accession P41220), corresponding to amino acid residues T36-E86.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Affinity chromatography
保存液
PBS, pH 7.4, with 50% glycerol
内含物
0.02% sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Antibody detects endogenous levels of total RGS2.
靶标信息
Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 2 belongs to this family. The protein acts as a mediator of myeloid differentiation and may play a role in leukemogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: cell growth-inhibiting gene 31 protein; cell growth-inhibiting protein 31; G0 to G1 switch regulatory 8, 24kD; G0/G1 switch regulatory protein 8; GIG31; regulator of G-protein signaling 2, 24kDa; regulator of G-protein signaling protein 2; RGS 2; RGS2; RGS2; GTPase activating protein for G-alpha subunits; RGS2; induced by PTH; unnamed protein product
基因别名: G0S8; GOS8
UniProt ID: (Human) P41220, (Rat) Q9JHX0, (Mouse) O08849
Entrez Gene ID: (Human) 5997, (Rat) 84583, (Mouse) 19735
response to amphetamine
G-protein coupled receptor signaling pathway
spermatogenesis
regulation of G-protein coupled receptor protein signaling pathway
negative regulation of cardiac muscle hypertrophy
positive regulation of neuron projection development
negative regulation of translation
response to ethanol
negative regulation of G-protein coupled receptor protein signaling pathway
negative regulation of JNK cascade
relaxation of cardiac muscle
relaxation of vascular smooth muscle
maternal process involved in female pregnancy
positive regulation of cardiac muscle contraction
negative regulation of cell growth involved in cardiac muscle cell development
regulation of adrenergic receptor signaling pathway
positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway
negative regulation of glycine import across plasma membrane
brown fat cell differentiation
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