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Invitrogen
RHD (Roledumab Biosimilar) Recombinant Human Monoclonal Antibody
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RHD (Roledumab Biosimilar) Antibody (MA5-41923) in SDS-PAGE
SDS-PAGE analysis of the recombinant Human RHD protein expressed in CHO cells using a RHD (Roledumab Biosimilar) monoclonal antibody (Product # MA5-41923). R denotes the lane was run under reducing conditions. NR denotes the lane was run under non-reducing conditions.
产品信息
MA5-41923
产品规格
种属反应
Human
宿主/亚型
Human
/ IgG1, kappa
Expression System
CHO cells
分类
Recombinant Monoclonal
类型
Antibody
抗原
Human RHD
偶联物
形式
Liquid
浓度
1.04 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Endotoxin level < 0.01EU/µg by LAL method
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 °C for one week. Store at -20 to -80 °C for twelve months from the date of receipt.
靶标信息
The Rhesus (Rh) blood group system represents one of the most complex and important systems in humans. Two highly homologous genes RHD and RHCE (collectively referred to as RH30 or RHCED) encode the antigens of the Rh blood group system (1-4). These tightly linked genes map to human chromosomal position 1p34.1-1p36. The RHD gene, which is commonly deleted from a large segment of the population, encodes the most potent blood group immunogen, the D antigen (2,5). Rh incompatibility between maternal and fetal blood types results in hemolytic disease of the newborn (HDN), which often results in fetal death (1,2,6). The RHCE gene exists in four allelic forms, and each allele determines the expression of two antigens in Ce, ce, cE, or CE combinations (2,4,5). The RHCED antigens exist as integral membrane proteins with contain 12-transmembrane helices, and maintain erythrocyte membrane integrity. The presentation of the Rh antigenic activity requires the formation of a complex between the RHCED antigens and RHAG (RH50).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: blood group antigen D; blood group protein RHD; Blood group Rh(D) polypeptide; CD240D; D antigen (DCS); Del(L18P) protein; mutation in the fifth exon with base deletions and insertion of T and C bases; Rh blood group antigen Evans; Rh blood group C antigen; Rh blood group CcEe antigen; Rh blood group D antigen weak D type 160; Rh blood group system D-antigen; Rh blood group, D anitgen; RH polypeptide 2; Rh polypeptide II; Rh(D) Blood-Group antigen; RHD; RhD antigen; RhD blood group antigen; RhD glycoprotein; RhD polypeptide; RhD protein; RHDVI type IV variant; Rhesus blood group antigen D; Rhesus D antigen; Rhesus D blood group protein; Rhesus system D polypeptide; Rhesus system D polypeptide; RH polypeptide 2; blood group Rh(D) polypeptide; D antigen (DCS); Rh blood group antigen Evans; rhesus D antigen; RhPII; RHXIII; unnamed protein product; weak D; weak RHD antigen
基因别名: CD240D; DIIIc; HDFNRH; RH; RH30; Rh4; RHCED; RHD; RhDCw; RHDel; RHDVA(TT); RhII; RhK562-II; RhPI; RHPII; RHXIII; SLC42A5
UniProt ID: (Human) Q02161
Entrez Gene ID: (Human) 6007
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