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Invitrogen
RIF1 Polyclonal Antibody
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FIGURE: 1 / 6
RIF1 Antibody (PA5-57857) in ICC/IF
Immunofluorescence analysis of RIF1 was performed using 70% confluent log phase NIH:OVCAR-3 cells. The cells were fixed with 4% paraformaldehyde for 10 minutes, permeabilized with 0.1% Triton™ X-100 for 15 minutes, and blocked with 2% BSA for 45 minutes at room temperature. The cells were labeled with RIF1 Polyclonal Antibody (Product # PA5-57857) at 1:200 in 0.1% BSA, incubated at 4 degree celsius overnight and then labeled with Donkey anti-Rabbit IgG (H+L) Highly Cross-Adsorbed Secondary Antibody, Alexa Fluor Plus 488 (Product # A32790),... View More
Product Details
PA5-57857
Applications
Tested Dilution
Publications
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit
/ IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human RIF1. Recombinant protein control fragment (Product #RP-95991).
Conjugate
Form
Liquid
Concentration
0.2 mg/mL
Amount
20 µg
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Ambient (domestic); Wet ice (international)
RRID
Product Specific Information
Immunogen sequence: ELNVGNEASF HGQERTKTGI SEEAAIEENK RNDDSEADTA KLNAKEVATE EFNSDISLSD NTTPVKLNAQ TEISEQTAAG ELDGGNDVSD LHSS
Highest antigen sequence identity to the following orthologs: Mouse - 38%, Rat - 36%.
Target Information
May have a role in sperm development and fertilization.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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Bioinformatics
Protein Aliases: DKFZp434D1026; DKFZp781N1478; FLJ12870; putative telomere length regulator; RAP1 interacting factor homolog; Rap1-interacting factor 1 homolog; Telomere-associated protein RIF1; unnamed protein product
Gene Aliases: RIF1
UniProt ID: (Human) Q5UIP0
Entrez Gene ID: (Human) 55183
negative regulation of transcription from RNA polymerase II promoter
telomere maintenance
DNA repair
cellular response to DNA damage stimulus
telomeric heterochromatin assembly
somatic stem cell population maintenance
telomere maintenance in response to DNA damage
negative regulation of gene expression, epigenetic
positive regulation of isotype switching
cellular response to leukemia inhibitory factor
negative regulation of double-strand break repair via homologous recombination
positive regulation of double-strand break repair via nonhomologous end joining
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Performance Guarantee
If an Invitrogen™ antibody doesn't perform as described on our website or datasheet,we'll replace the product at no cost to you, or provide you with a credit for a future purchase.*
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