Invitrogen

RIPK5 Polyclonal Antibody

Name: RIPK5 Polyclonal Antibody
Brand: Invitrogen
SKU: PA5-60625

高级验证

查看其他12个RIPK5抗体

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

说明书

实验方案

问题与答案

技术支持

抗体检测数据 (1)
高级验证 (1)

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RIPK5 Antibody (PA5-60625) in WB

Western blot analysis of RIPK5 in human cell lines SK-MEL-30 and Caco-2 using a RIPK5 Polyclonal Antibody (Product # PA5-60625). Corresponding DSTYK RNA-seq data are presented for the same cell lines. Loading control: Anti-HDAC1.

Product Image Gallery

RIPK5 Antibody — Relative expression in western blot: Antibody specificity was demonstrated by detection of known differential basal expression of the target across tissue/cell models. Expression of RIPK5 was observed specifically in SK-MEL-30 cells and in Caco-2 cells using anti-RIPK5 Polyclonal Antibody (Product # PA5-60625) in western blot. The relative expression levels of RIPK5 within each cell line is shown using RNA-Seq. {RE}

Immunogen image

Immunogen Image RIPK5 Polyclonal Antibody

产品信息

PA5-60625

应用

建议稀释比

已发表文章

免疫印迹 (WB)

0.04-0.4 µg/mL

产品规格

种属反应

Human

宿主/亚型

Rabbit / IgG

分类

Polyclonal

类型

Antibody

抗原

Recombinant protein corresponding to Human RIPK5. Recombinant protein control fragment (Product #RP-89784).

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偶联物

Unconjugated Unconjugated Unconjugated

形式

Liquid

浓度

0.2 mg/mL

纯化类型

Antigen affinity chromatography

保存液

PBS, pH 7.2, with 40% glycerol

内含物

0.02% sodium azide

保存条件

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

运输条件

Ambient (domestic); Wet ice (international)

AB_2646579

产品详细信息

Immunogen sequence: KENELYESLM NIANRKQEEM KDMIVETLNT MKEELLDDAT NMEFKDVIVP ENGEPVGTRE IKCCIRQIQE LIISRLNQAV ANKLISSVDY LRESFVGTLE RCLQSLEKSQ DVSVHITSNY LKQILNAAYH VEVTFHSGSS

Highest antigen sequence identity to the following orthologs: Mouse - 97%, Rat - 98%.

靶标信息

RIPK5 is a serine/threonine kinase that is involved in cell activation, proliferation, differentiation, and apoptosis. This gene encodes a dual serine/threonine and tyrosine protein kinase which is expressed in multiple tissues. Multiple transcript variants encoding different isoforms have been found for this gene.

仅用于科研。不用于诊断过程。未经明确授权不得转售。

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引用该产品

生物信息学

蛋白别名: Dual serine/threonine and tyrosine protein kinase; Dusty PK; Dusty protein kinase; Receptor-interacting serine/threonine-protein kinase 5; RIP-homologous kinase; SgK496; Sugen kinase 496

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基因别名: CAKUT1; DSTYK; DustyPK; HDCMD38P; KIAA0472; RIP5; RIPK5; SGK496

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UniProt ID: (Human) Q6XUX3

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Entrez Gene ID: (Human) 25778

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功能

protein serine/threonine kinase activity protein serine/threonine/tyrosine kinase activity protein tyrosine kinase activity ATP binding non-receptor serine/threonine protein kinase protein modifying enzyme

参与通路

peptidyl-tyrosine phosphorylation positive regulation of kinase activity cellular response to fibroblast growth factor stimulus positive regulation of fibroblast growth factor receptor signaling pathway positive regulation of ERK1 and ERK2 cascade