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Invitrogen
RITA1 Polyclonal Antibody
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产品信息
PA5-58654
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.2 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: AGPSKTEPGP AADSQKLSMG GLHSSRPLKR GLSHSLTHLN VPSTGHPATS APHTNGPQDL RPSTSGVTFR SPLVTSRARS VSISVPST
Highest antigen sequence identity to the following orthologs: Mouse - 59%, Rat - 56%.
靶标信息
Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: RBPJ-interacting and tubulin-associated protein; RBPJ-interacting and tubulin-associated protein 1
基因别名: C12orf52; PSEC0043; RITA; RITA1
UniProt ID: (Human) Q96K30
Entrez Gene ID: (Human) 84934
