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Invitrogen
RMI2 Polyclonal Antibody
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RMI2 Antibody (PA5-95632) in IHC (P)
Immunohistochemical analysis of RMI2 in paraffin-embedded section of mouse liver tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1μg/mL rabbit anti-RMI2 antibody (Product # PA5-95632) overnight at 4°C. Biotinylated goat anti-rabbit IgG was use... View More
产品信息
PA5-95632
应用
建议稀释比
已发表文章
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
A synthetic peptide corresponding to a sequence of human RMI2 (KMTDLSDNPIHESMWELEVEDLHRNIP).
偶联物
形式
Lyophilized
浓度
500 µg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS with 4mg trehalose
内含物
0.05mg sodium azide
保存条件
-20°C
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Positive Control - WB: human Hela whole cell, human T-47D whole cell, human HepG2 whole cell, human K562 whole cell, rat thymus tissue, mouse HEPA1-6 whole cell. IHC: human intestinal cancer tissue, human intestinal cancer tissue, rat liver tissue, human mammary cancer tissue, human mammary cancer tissue, mouse liver tissue. Flow: U20S cell.|Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
靶标信息
RMI2 is a protein coding gene, essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates. It is required to regulate sister chromatid segregation and to limit DNA crossover. Essential for the stability, localization, and function of BLM, TOP3A, and complexes containing BLM. In the RMI complex, it is required to target BLM to chromatin and stress-induced nuclear foci and mitotic phosphorylation of BLM.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: BLAP18; BLM-associated protein of 18 kDa; hRMI2; RecQ mediated genome instability 2; RecQ-mediated genome instability protein 2; RMI2, RecQ mediated genome instability 2, homolog
基因别名: A630055G03Rik; BLAP18; C16orf75; Gm537; Gm929; RGD1563163; RMI2
UniProt ID: (Human) Q96E14, (Mouse) Q3UPE3
Entrez Gene ID: (Human) 116028, (Rat) 497856, (Mouse) 223970
