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Abnova
RNASEL Monoclonal Antibody (3B4)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00006041-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG1, kappa
分类
Monoclonal
类型
Antibody
克隆号
3B4
抗原
RNASEL (NP_066956, 619 a.a. approximately 728 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: QPGPSEHSKS FDKWTTKINE CVMKKMNKFY EKRGNFYQNT VGDLLKFIRN LGEHIDEEKH KKMKLKIGDP SLYFQKTFPD LVIYVYTKLQ NTEYRKHFPQ THSPNKPQCD
靶标信息
A virally induced endoribonuclease, RNase L is the terminal factor of the anti-viral action of interferon. Activation of RNase L results in inhibition of viral proliferation. Activation of RNase L has also been determined to degrade RNA, thus, initiating a cellular stress response, inducing apoptosis. Since mutations in RNase L relate to an increased incidence of prostate cancer, the activation of RNase L functions in counteracting prostate cancer, via apoptosis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 2',5'-oligoisoadenylate synthetase-dependent; 2',5'-oligoisoadenylate synthetase-dependent; endoribonuclease; 2-5A-dependent RNase; interferon-induced 2-5A-dependent RNase; ribonuclease 4; RNase L
基因别名: PRCA1; RNS4
UniProt ID: (Human) Q05823
Entrez Gene ID: (Human) 6041
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