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Abnova
RNF17 Monoclonal Antibody (1E3)
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产品信息
H00056163-M01
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2a, kappa
分类
Monoclonal
类型
Antibody
克隆号
1E3
抗原
RNF17 (NP_112567, 30 a.a. approximately 139 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
形式
Liquid
浓度
0.5 mg/mL
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Sandwich ELISA (Recombinant protein).
Immunogen sequence: IQCTRCGRRV SRSSGHHCEL QCGHAFCELC LLMTEECTTI ICPDCEVATA VNTRQRYYPM AGYIKEDSIM EKLQPKTIKN CSQDFKKTAD QLTTGLERSA STDKTLLNSS
靶标信息
RNF17 also termed as ring finger protein 17 is a 1623 amino acid protein, which contains 1 ring type zinc finger and 4 tudor domains. RNF17 is specifically expressed in testis. The RING finger motif presents in many ubiquitin E3 ligases. RNF17 interacts with all four members of the Mad family (Mad1, Mxi1, Mad3 and Mad4), which are basic-helix-loop-helix-leucine zipper transcription factors of the Myc oncoprotein network. RNF17 is component of the tectonic-like complex, which is required for ciliogenesis and sonic hedgehog/SHH signaling. RNF17 is able to form dimers or polymers both in vitro and in vivo, indicating that it may play a role in the assembly of RNF17 granules. RNF17 encodes a novel key regulator of spermiogenesis.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: RING finger protein 17; spermatogenesis associated 23; tudor domain containing 4; Tudor domain-containing protein 4
基因别名: Mmip-2; RNF17; SPATA23; TDRD4
UniProt ID: (Human) Q9BXT8
Entrez Gene ID: (Human) 56163
