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Invitrogen
RNF182 Polyclonal Antibody
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产品信息
PA5-52925
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7.2, with 40% glycerol
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Immunogen sequence: VLECCHRVCA KCLYKIIDFG DSPQGVIVCP FCRFETCLPD DEVSSLPDDN NILVNLTCGG KGKKCLPENP TELLLTPKRL ASLVSPSHTS SNCLVITIME VQRESSPSLS STPVVEFYRP ASFDSVTTVS HNWTVWNCTS LL
Highest antigen sequence identity to the following orthologs: Mouse - 100%, Rat - 99%.
靶标信息
E3 ubiquitin-protein ligase that mediates the ubiquitination of ATP6V0C and targets it to degradation via the ubiquitin-proteasome pathway (PubMed:18298843). Plays also a role in the inhibition of TLR-triggered innate immune response by mediating 'Lys'-48-linked ubiquitination and subsequent degradation of NF-kappa-B component RELA (PubMed:31432514). [UniProt]
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: E3 ubiquitin-protein ligase RNF182; RING finger protein 182; RING-type E3 ubiquitin transferase RNF182
基因别名: RNF182
UniProt ID: (Human) Q8N6D2
Entrez Gene ID: (Human) 221687
