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Invitrogen
RNF213 Polyclonal Antibody
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RNF213 Antibody (PA5151275) in IHC (P)
Immunohistochemistry analysis of RNF213 in paraffin-embedded human colon. Samples were incubated with RNF213 polyclonal (Product # PA5151275) using a dilution of 1:200, followed by Donkey anti-Rabbit-Cy3 at a dilution of 1:200. Magnification was set at 20X; Exposure Time: 0.5-2.0 sec.
Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
PA5151275
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
The immunogen is a synthetic peptide directed towards the N terminal region of human KIaa 1618.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
50 µg
纯化类型
Affinity chromatography
保存液
PBS with 2% sucrose
内含物
0.09% sodium azide
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
靶标信息
RNF213 is an E3 ubiquitin-protein ligase involved in angiogenesis. Involved in the non-canonical Wnt signaling pathway in vascular development: acts by mediating ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression. Also has ATPase activity.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: ALK lymphoma oligomerization on chromosome 17; ALK lymphoma oligomerization partner on chromosome 17; E3 ubiquitin-lipopolysaccharide ligase RNF213; mysterin; RING-type E3 ubiquitin transferase RNF213; unnamed protein product
基因别名: ALO17; C17orf27; KIAA1618; MYMY2; MYSTR; NET57
UniProt ID: (Human) Q63HN8
Entrez Gene ID: (Human) 57674
angiogenesis
sprouting angiogenesis
ubiquitin-dependent protein catabolic process
protein ubiquitination
regulation of lipid metabolic process
defense response to bacterium
protein autoubiquitination
protein K63-linked ubiquitination
xenophagy
lipid ubiquitination
lipid droplet formation
negative regulation of non-canonical Wnt signaling pathway
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