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Invitrogen
RNF6 Polyclonal Antibody
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产品信息
PA5-28442
产品规格
种属反应
Human
宿主/亚型
Rabbit
/ IgG
分类
Polyclonal
类型
Antibody
抗原
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human RNF6. The exact sequence is proprietary.
偶联物
形式
Liquid
浓度
0.86 mg/mL
纯化类型
Antigen affinity chromatography
保存液
PBS, pH 7, with 10% glycerol
内含物
0.01% thimerosal
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recommended positive controls: 293T, A431, H1299, HeLa, HepG2, Molt-4.
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
靶标信息
The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.
⚠WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm. For more information go to www.P65Warnings.ca.gov.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: DKFZp686P0776; E3 ubiquitin-protein ligase RNF6; ring finger protein (C3H2C3 type) 6; RING-H2 protein RNF-6
基因别名: RNF6; SPG2
UniProt ID: (Human) Q9Y252
Entrez Gene ID: (Human) 6049
regulation of transcription, DNA-templated
ubiquitin-dependent protein catabolic process
negative regulation of axon extension
proteasome-mediated ubiquitin-dependent protein catabolic process
protein K27-linked ubiquitination
positive regulation of transcription, DNA-templated
regulation of androgen receptor signaling pathway
protein K48-linked ubiquitination
protein K6-linked ubiquitination
