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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: SGTVYHNSQR ESRPVQQTTR RSVRRRGRTR VFLEQDRERE RRGTAYTPFS NSRLVSRITV EEGEESSRSS TAVRR
Highest antigen sequence identity to the following orthologs: Mouse - 76%, Rat - 72%.
The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed.
仅用于科研。不用于诊断过程。未经明确授权不得转售。