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A suggested positive control is Jurkat cell lysate.
PA5-20326 can be used with blocking peptide PEP-0446.
Replication protein A (RPA) is a single-stranded-DNA binding protein involved in numerous eukaryotic DNA processes including replication, repair and recombination. RPA interacting protein (RPA IP) has been identified as an adapter protein that is involved in RPA nuclear import instead of the prototypical importin proteins that normally mediate nuclear import. Multiple isoforms of RPA IP are known to exist, with the longest isoform localized to the cytoplasm. Isoform 2 is sumoylated and is located in the PML nuclear body within the nucleus. It has been suggested that this isoform mediates the localization of the RPA complex into the PML nuclear body, thereby participating in RPA function in DNA metabolism.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: hRIP; nuclear transporter; RAP interaction protein; RAP interaction protein alpha; RPA interacting protein delta 2; RPA interacting protein epsilon; RPA-interacting protein
基因别名: 2400006N03Rik; HRIP; RGD1308492; RIP; RPAIN
UniProt ID: (Human) Q9BT00, (Mouse) Q9CWY9, (Rat) Q4G2Y1
Entrez Gene ID: (Human) 84268, (Mouse) 69723, (Rat) 287463