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Invitrogen
RPS3 Recombinant Rabbit Monoclonal Antibody (SA46-08)
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产品信息
MA5-31973
产品规格
种属反应
Human,
Mouse,
Rat
宿主/亚型
Rabbit
/ IgG
Expression System
HEK293 cells
分类
Recombinant Monoclonal
类型
Antibody
克隆号
SA46-08
抗原
Synthetic peptide within Human RPS3 aa 125-174.
偶联物
形式
Liquid
浓度
1 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
TBS, pH 7.4, with 40% Glycerol, 0.05% BSA
内含物
0.05% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
产品详细信息
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems. The expression systems are developed by cloning in the specific antibody DNA sequences from immunoreactive rabbits. Then, individual clones are screened to select the best candidates for production. The advantages of using recombinant rabbit monoclonal antibodies include: better specificity and sensitivity, lot-to-lot consistency, animal origin-free formulations, and broader immunoreactivity to diverse targets due to larger rabbit immune repertoire.
靶标信息
WD repeat domain 5 (WDR5) is a member of the WD repeat protein family, which is involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. WDR5, also known as BIG-3, is expressed in the developing growth plate, accelerates chondrocyte and osteoblast differentiation in vitro, and regulates osteoblast differentiation during embryonic bone development. WDR5 interacts with the pluripotency factor Oct4/POU5F1 and is required for the efficient formation of induced pluripotent stem (iPS) cells.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: 40S ribosomal protein S3; FLJ26283; FLJ27450; IMR-90 ribosomal protein S3; MGC87870; OTTHUMP00000229804; OTTHUMP00000229805; OTTHUMP00000229874; OTTHUMP00000229877; OTTHUMP00000229878; OTTHUMP00000229879; OTTHUMP00000229880; OTTHUMP00000229882; OTTHUMP00000229883; OTTHUMP00000229886; Small ribosomal subunit protein uS3; unnamed protein product
基因别名: D7Ertd795e; OK/SW-cl.26; RPS3; Rs_3; S3; uS3
UniProt ID: (Human) P23396, (Mouse) P62908, (Rat) P17073
Entrez Gene ID: (Human) 6188, (Mouse) 27050, (Rat) 140654
RNA polymerase II regulatory region sequence-specific DNA binding
DNA binding
damaged DNA binding
RNA binding
mRNA binding
structural constituent of ribosome
DNA-(apurinic or apyrimidinic site) lyase activity
endodeoxyribonuclease activity
protein binding
microtubule binding
tubulin binding
lyase activity
DNA N-glycosylase activity
enzyme binding
kinase binding
protein kinase binding
Hsp70 protein binding
oxidized purine DNA binding
oxidized pyrimidine DNA binding
ubiquitin-like protein conjugating enzyme binding
macromolecular complex binding
protein kinase A binding
iron-sulfur cluster binding
Hsp90 protein binding
small ribosomal subunit rRNA binding
supercoiled DNA binding
class I DNA-(apurinic or apyrimidinic site) endonuclease activity
DNA-binding transcription factor binding
nucleic acid binding
oxidized purine nucleobase lesion DNA N-glycosylase activity
poly(A) RNA binding
NF-kappaB binding
ribosomal protein
cytoplasmic translation
DNA repair
base-excision repair
translation
translational initiation
regulation of translation
apoptotic process
cellular response to DNA damage stimulus
chromosome segregation
positive regulation of gene expression
negative regulation of translation
positive regulation of microtubule polymerization
positive regulation of protein complex assembly
negative regulation of protein ubiquitination
positive regulation of endodeoxyribonuclease activity
positive regulation of interleukin-2 production
cellular response to reactive oxygen species
positive regulation of activated T cell proliferation
regulation of apoptotic process
negative regulation of DNA repair
positive regulation of DNA repair
positive regulation of T cell receptor signaling pathway
positive regulation of NF-kappaB transcription factor activity
spindle assembly
cell division
response to TNF agonist
cellular response to hydrogen peroxide
cellular response to tumor necrosis factor
positive regulation of NIK/NF-kappaB signaling
positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage
positive regulation of base-excision repair
positive regulation of apoptotic signaling pathway
DNA metabolic process
transcription, DNA-templated
regulation of transcription, DNA-templated
cell cycle
mitotic nuclear division
nucleic acid phosphodiester bond hydrolysis
positive regulation of DNA N-glycosylase activity
DNA catabolic process, endonucleolytic
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