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Antibody detects endogenous levels of total RPS4Y1.
Cytoplasmic ribosomes, organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes ribosomal protein S4, a component of the 40S subunit. Ribosomal protein S4 is the only ribosomal protein known to be encoded by more than one gene, namely this gene and ribosomal protein S4, X-linked (RPS4X). The 2 isoforms encoded by these genes are not identical, but are functionally equivalent. Ribosomal protein S4 belongs to the S4E family of ribosomal proteins. It has been suggested that haploinsufficiency of the ribosomal protein S4 genes plays a role in Turner syndrome; however, this hypothesis is controversial. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: 40S ribosomal protein S4; 40S ribosomal protein S4, Y; ribosomal protein S4Y; Small ribosomal subunit protein eS4, Y isoform 1
基因别名: PRO2646; RPS4Y; RPS4Y1; S4
UniProt ID: (Human) P22090
Entrez Gene ID: (Human) 6192