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Abnova
RPS6KA3 Monoclonal Antibody (2G10)
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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
产品信息
H00006197-M01
应用
建议稀释比
已发表文章
产品规格
种属反应
Human
宿主/亚型
Mouse
/ IgG2b, kappa
分类
Monoclonal
类型
Antibody
克隆号
2G10
抗原
RPS6KA3 (NP_004577, 2 a.a. approximately 95 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
偶联物
Unconjugated
Unconjugated
Unconjugated
形式
Liquid
浓度
0.5 mg/mL
规格
100 µg
纯化类型
Protein A
保存液
PBS, pH 7.4
内含物
no preservative
保存条件
-20°C, Avoid Freeze/Thaw Cycles
运输条件
Ambient (domestic); Wet ice (international)
产品详细信息
Product may be used with Western Blot (Cell lysate).
Immunogen sequence: PLAQLADPWQ KMAVESPSDS AENGQQIMDE PMGEEEINPQ TEEVSIKEIA ITHHVKEGHE KADPSQFELL KVLGQGSFGK VFLVKKISGS DARQ
靶标信息
RPS6KA3 (RSK2) is a serine/threonine kinase that modulates many cellular processes including transcription, adhesion, growth, survival, and proliferation. RPS6KA3 contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Mutations in the gene have been associated with Coffin-Lowry syndrome (CLS).
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: epididymis secretory sperm binding protein; insulin-stimulated protein kinase 1; MAP kinase-activated protein kinase 1b; MAPK-activated protein kinase 1b; MAPKAP kinase 1b; MAPKAPK-1b; p90-RSK 3; ribosomal protein S6 kinase, 90kDa, polypeptide 3; ribosomal S6 kinase 2; RPS6KA3; RSK-2; S6K-alpha-3; unnamed protein product
基因别名: CLS; HU-3; ISPK-1; MAPKAPK1B; MRX19; p90-RSK2; pp90RSK2; RSK; RSK2; S6K-alpha3; XLID19
UniProt ID: (Human) P51812
Entrez Gene ID: (Human) 6197
skeletal system development
toll-like receptor signaling pathway
regulation of transcription, DNA-templated
signal transduction
chemical synaptic transmission
central nervous system development
positive regulation of cell growth
response to lipopolysaccharide
intracellular signal transduction
TORC1 signaling
negative regulation of apoptotic process
regulation of translation in response to stress
positive regulation of cell differentiation
positive regulation of transcription from RNA polymerase II promoter
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