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Invitrogen
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Peptide sequence: IDIFTSNTYV MVVMSDPSIP SAATLINIRN ARKHFEKLER VDGPKQCLLM
Sequence homology: Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Sheep: 100%; Zebrafish: 93%
Ras-homologous GTPases constitute a large family of signal transducers that alternate between an activated, GTP-binding state and an inactivated, GDP-binding state. These proteins represent cellular switches that are operated by GTP-exchange factors and factors that stimulate their intrinsic GTPase activity. All GTPases of the Ras superfamily have in common the presence of six conserved motifs involved in GTP/GDP binding, three of which are phosphate-/magnesium-binding sites (PM1-PM3) and three of which are guanine nucleotide-binding sites (G1-G3). Transcript variants encoding distinct isoforms have been identified.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: GTP-binding protein ragB; Rag B; Ras-related GTP binding B; Ras-related GTP-binding protein B; RRAGB
基因别名: bA465E19.1; RAGB; RRAGB
UniProt ID: (Human) Q5VZM2
Entrez Gene ID: (Human) 10325