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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Antibody detects endogenous levels of total RSF1.
RSF1 is required for assembly of regular nucleosome arrays by the RSF chromatin remodelling complex. Rsf1 facilitates transcription of hepatitis B virus (HBV) genes by the pX transcription activator. In case of infection by HBV, together with pX, it represses TNF-alpha induced NF-kappaB transcription activation. Rsf1 represses transcription when artificially recruited to chromatin by fusion to a heterogeneous DNA binding domain. Rsf1 interacts with SMARCA5/SNF2H to form the RSF complex and also binds the HBV pX/HBx protein, which is required to activate transcription of the viral genome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HBV pX-associated protein 8; hepatitis B virus x associated protein; Hepatitis B virus X-associated protein; p325 subunit of RSF chromatin-remodeling complex; Remodeling and spacing factor 1; Rsf-1
基因别名: 4832420A03Rik; C030033M12Rik; Gm164; HBXAP; p325; RSF1; XAP8
Entrez Gene ID: (Mouse) 233532, (Rat) 308839