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Please note: We are reviewing Western blot images included in the antibody testing data in our catalog, including those provided by third parties. Unless expressly labeled or annotated as “raw-unedited”, Western blot images included in the antibody testing data in our catalog may have been edited, optimized or otherwise adjusted for presentation.
Immunogen sequence: KYLCECQFDD NLKFKNIINE EDADTMRLQP IGRDKDGLMY WYQLDQDHNV RMYIEEQDDQ DGSSWKCIVR NRNELAETLA LLKAQIDPVL LK
Highest antigen sequence indentity to the following orthologs: Rat - 99%, Mouse - 100%.
RSF1 is required for assembly of regular nucleosome arrays by the RSF chromatin remodelling complex. Rsf1 facilitates transcription of hepatitis B virus (HBV) genes by the pX transcription activator. In case of infection by HBV, together with pX, it represses TNF-alpha induced NF-kappaB transcription activation. Rsf1 represses transcription when artificially recruited to chromatin by fusion to a heterogeneous DNA binding domain. Rsf1 interacts with SMARCA5/SNF2H to form the RSF complex and also binds the HBV pX/HBx protein, which is required to activate transcription of the viral genome.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: HBV pX-associated protein 8; Hepatitis B virus X-associated protein; p325 subunit of RSF chromatin-remodeling complex; Remodeling and spacing factor 1; Rsf-1
基因别名: HBXAP; RSF1; XAP8
Entrez Gene ID: (Human) 51773