Search Thermo Fisher Scientific
Additional Information: This antibody is expected to recognize both reported isoforms (NP_066958.2; NP_001006933.1).
This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:64,000.
RPS6KA2 (RSK3) serine/threonine kinase is a member of the ribosomal S6 kinase (RSK) family. It is believed that RPS6KA2 is a signal-transducing intermediate in the cellular response to several growth factors. It is found in many tissues, but in higher levels in lung and skeletal muscle. The p90 ribosomal S6 kinases (RSK)1-4 are downstream members of the extracellular signal-regulated kinase (ERK)/MAPK cascade. The loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, which is characterized by mental retardation and growth deficits and may have a tonic regulation on G-protein coupled signaling.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
蛋白别名: ribosomal protein S6 kinase alpha-2; ribosomal protein S6 kinase, 90kD, polypeptide 2
Entrez Gene ID: (Rat) 117269
分子生物学功能: protein modifying enzyme