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Invitrogen
RT1.A Monoclonal Antibody (OX-18), Biotin
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产品信息
MA5-17409
产品规格
种属反应
Rat
宿主/亚型
Mouse
/ IgG1
分类
Monoclonal
类型
Antibody
克隆号
OX-18
抗原
rat spleen membrane glycoproteins depleted of Ia-A antigens
偶联物
形式
Liquid
浓度
0.1 mg/mL
纯化类型
Protein G
保存液
PBS with 4-5mg/mL BSA
内含物
0.02% sodium azide
保存条件
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
运输条件
Ambient (domestic); Wet ice (international)
RRID
靶标信息
This protein is a non-polymorphic determinant of rat MHC Class I, which is also known as RT1-A. Rat MHC Class I is expressed on all nucleated cells and erythrocytes.
HLA and MHC antibodies play a significant role in Immunopeptidomics, facilitating the identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem Mass Spectrometry.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
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生物信息学
蛋白别名: HA11; MHC class I RT1.Aa alpha-chain; Rat class I A; RT1 class I gene (A-1); RT1 class Ia, locus A (A1); RT1 class Ia, locus A1; RT1-A; RT1-AW2
基因别名: RT1.A1(N); RT1A-1
Entrez Gene ID: (Rat) 24973, (Rat) 100188935
positive regulation of T cell mediated cytotoxicity
antigen processing and presentation of peptide antigen via MHC class I
T cell tolerance induction
positive regulation of tolerance induction to nonself antigen
immune response
negative regulation of natural killer cell mediated cytotoxicity
antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
